CD11b Antikörper

Produktnummer ABIN375583

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD11b in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD11b Antikörper (ABIN375583)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: ICRF44

Produktdetails anti-CD11b Antikörper

Spezifität: Human/Porcine/Rhesus/Cynomolgus/Chimpanzee/Baboon CD11b, Mr 165 kDa

Produktmerkmale: Mouse Anti-Human CD11b-UNLB

Aufreinigung: Purified

Immunogen: Rheumatoid synovial cells and human monocytes

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, SPRD, PACBLU, AF488 and AF647 10 L/106 cells conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

Blocking Studies

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: CD11b

Hintergrund: CD11b is the 165 kDa α M chain which combines with the CD18 β 2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b/Mac-1 α functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation